Systematic Lupus Erythromatus

Abstract

Background : Systemic lupus erythematosus (SLE) is a relapsing and unpredictable multisystem disease. The exact cause is unknown, although it appears to result from an immunoregulatory disturbance brought about by combination of genetic, hormonal, chemical, and environment factors. The major symptoms of SLE aremalar rash, discoid rash, photosensitivity, oral ulcers, arthritis, serositis, renal manifestations, neurological manifestations, haematological manifestations, immunological manifestations or a positive antinuclear antibody (ANA) result. Diagnostic criteria based on major criteria of SLE. Prognosis is good if the disease is controlled during the initial acute phase. Treatment depends on the severity of the disease as well as organ involved. In case of mild symptoms require the use of NSAIDS and in severe form require corticosteroids or immunosupressants. Therefore, SLE patients require a healthcare team of multiple disciplines and professions, with close monitoring and control to prevent the worsening of the disease or the development of complications. Case presentation: case of 25-year-old female patient present to the hospital with progressive difficulty in breathing, chest pain, generalized edema, joint pain, alopecia, severe fatigue and sleep disturbance over the 6 month which is diagnosed as systemic lupus erythematosus

Conclusions: SLE is a chronic, autoimmune disease which induce renal, digestive, neurologic and hematologic disorders. It is characterized by erythema, myalgia and arthralgias. For prevention of complication, multidisciplinary health professional team is required.